Smart Mice: Web Extra Video ScienCentral News – New York,NY,USA Researcher James Bibb and his team were on a mission to learn more about the role of the gene Cdk5 in brain function. When they turned off this gene in mice …
NIH Link
GeneID: 1020 updated 03-Jun-2007
Official Symbol
CDK5provided by HGNC
Official Full Name
cyclin-dependent kinase 5provided by HGNC
Primary source
HGNC:1774
See related
HPRD:00449; MIM:123831
Gene type
protein coding
RefSeq status
Validated
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PSSALRE
“Smart” Gene Discovered: Accelerates learning and memory By Lincoln @ MaRS The researchers genetically engineered mice with an inactivated Cdk5 gene, which is involved in neural communication in the brain. “What we’ve found is a whole new mechanism of how learning and memory is controlled,” said UT …
ScienCentral News – New York,NY,USA Bibb wanted to study the Cdk5 gene because it is suspected to be involved in Alzheimer’s disease as well as in drug addictions. …
Scientists Make Smarter Mice
Animal Lab News – Amherst,NH,USA
The team, led by Dr. James Bibb, bred genetically engineered mice who could
be manipulated to turn off Cdk5, the gene that is linked to diseases such
as …
<http://www.animallab.com/News_Articles.asp?pid=183>
Mice With Single Neuronal Gene Turned Off Are Smarter
MedPage Today – Little Falls,NJ,USA
The key player in the experiments is a neuronal [...]
Scientists find new mechanism of learning in the brain
South Asian Women’s Forum – New Delhi,India
The researchers genetically engineered mice to lack an enzyme called Cdk5
in their brains by using the technique called ‘conditional knockout’,
…. Smart mice miss out on Alzheimer’s
News-Medical.net – Sydney,Australia
The specially bred rodents were genetically engineered without the enzyme
Cdk5 which [...]
Increased intelligence through genetic engineering
DrugResearcher.com – Montpellier,France
Cdk5 works with another a protease called calpain, to break up NMDA
receptor 2B (NR2B), which is found in nerve-cell membranes and stimulates
the cell to … Mice genetically engineered to lack a single enzyme in their …
By Adam Lawson(Adam Lawson)
In addition, Cdk5 is heavily implicated in Alzheimer’s disease and addiction [...]