“In our study, we employ mice to show that extinction of learned fear depends on counteracting components of a molecular pathway involving the protein kinase Cdk5. We found that Cdk5 activity prevents extinction, at least in part by …
Led by Li-Huei Tsai, Picower Professor of Neuroscience at MIT, the scientists showed that inhibiting an enzyme called Cdk5 (a protein kinase) in the hippocampus, the centre in the brain that stores emotional memories, …
Li-Huei Tsai, Picower Professor of Neuroscience in the Department of Brain and Cognitive Sciences, and colleagues show that inhibiting a kinase (kinases are enzymes that change proteins) called Cdk5 facilitates the extinction of fear …