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Monthly Archives: December 2007

Phosphatidylcholine Biosynthesis via CTP

[Lipids and Lipoproteins] Phosphatidylcholine Biosynthesis via CTP …
By Carter, J. M., Demizieux, L., Campenot,…
However, inhibition of Cdk5 by roscovitine blocked CTβ2 phosphorylation and reduced neurite outgrowth and branching. These results highlight the importance of CTβ2 in neurons for promoting neurite outgrowth and branching and represent …
<http://www.jbc.org/cgi/content/short/283/1/202>
Journal of Biological Chemistry…
<http://www.jbc.org>

Absence of CASK Protein May Lead To Autism

Absence of CASK Protein May Lead To Autism
Medi News Direct – Bangalore,Karnataka,India
The team suggested that cdk5 promotes synapse formation by interacting with
synapse-inducing proteins such as CASK. They concluded that Cdk5-mediated

<http://www.medinewsdirect.com/?p=370>
Tau-protein kinase
By tubious
Other names in common use include ATP:tau-protein O-hosphotransferase, brain protein kinase PK40erk, cdk5/p20, CDK5/p23, glycogen synthase kinase-3beta, GSK, protein tau kinase, STK31, [...]

Deregulation of CDK5 in Alzheimers Disease

BioCarta – Charting Pathways of Life
Inhibition of cdk5 or calpain activity reduces cell death in A beta-treated
… A survey of Cdk5 activator p35 and p25 levels in Alzheimers disease
brains. …
<http://www.biocarta.com/pathfiles/m_p35alzheimersPathway.asp>
UniProtKB/Swiss-Prot entry Q00535 [CDK5_HUMAN] Cell division …
“Apoptosis-associated tyrosine kinase is a Cdk5 activator p35 binding
protein.”; Biochem. Biophys. Res. Commun. 310:398-404(2003). …
<http://expasy.org/uniprot/Q00535>
cdk5
<http://genome-www.stanford.edu/cgi-bin/genecards/carddisp?CDK5>